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On 3 March 2022, Alkarama addressed the UN Working Group on Enforced Disappearances regarding the situation of Omar Maher Abdel Zaher EL DESOUKY, an Egyptian engineer who was arrested without a judicial warrant by security forces at Cairo airport on 20 December 2021 while on his way to Sweden.

On 24 February 2022, Alkarama addressed the UN Committee on Enforced Disappearances regarding the situation of three Iraqi brothers Aqil Khalil Hamid Ibrahim, Emad Khalil Hamid Ibrahim and Falah Khalil Hamid Ibrahim who were arrested at their home on 31 January 2014 by the military and have been missing since. While their family lost hope of finding them alive, one of the three brothers was seen in a detention center

Alkarama supports the call of the UN expert on the situation of human rights in Sudan, Adama Diang, to end the excessive use of force against peaceful protesters, lift the state of emergency in the country, release all remaining protesters and activists as well as investigate promptly and impartially all allegations of human rights violations.

On 22 February 2022, Alkarama addressed to the Special Rapporteur on the independence of judges and lawyers to inform him of the threats and intimidation to which the Lebanese lawyer Tarek Chindeb, known for his commitment to defend human rights in his country, is subjected.

"I am not afraid of justice but of injustice", wrote the former President of the Comoros, Mr. Ahmed Mohamed Abdallah Sambi, in a letter addressed to President Azali Assoumani, to underline a legal situation that is unprecedented in the history of Comorian justice.

Alkarama has learned that Saudi authorities have arbitrarily sentenced reformist preacher Khaled Al-Rashed to an additional eight-year imprisonment.  The heavy additional sentence comes 17 months after he completed his initial 15-year prison sentence

On February 16th, 2022, Alkarama addressed the UN Special Rapporteur on Torture regarding the case of the former governor of Qalyubia, who was arrested on September 17th, 2013 by the police and has been held in solitary confinement since then.

Political activist and former deputy minister of war victims and missing persons, Dr.  Abdurahman Mohamed Arjili Ghoma has been released, six years after his abduction in Libya.

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