On 25 November 2015, Alkarama wrote to several United Nations Special Procedures to encourage them to request a visit to Syria in order to raise the issues of enforced disappearance, torture and arbitrary detention.

On 22 November 2015, 43-year-old Arabic literature professor, Salah Salem Slimane Al Hassi was abducted from his home in Bayda City by members of an armed group loyal to General Khalifa Haftar. According to his family, Al Hassi's abduction took place in retaliation for having taken part in a peaceful demonstration a few days earlier. Al Hassi had joined this political protest in an effort to denounce the human rights violations regularly committed by General Haftar's militias in the city of Bayda, in eastern Libya.

In October 2012, Fadhil Othman, a 31-year-old concierge from Qamishli – a city in north-eastern Syria on the border with Turkey – disappeared from the national hospital where he was being treated after being shot by members of the Military Security at a checkpoint.

On 8 July 2015, Hasan Mohammed Hasan Al Essa, a 35-year-old Palestinian refugee, disappeared following his arrest by members of the security forces at his workplace, an aluminium factory in the Al Jadida neighbourhood in Baghdad. Still missing after almost five months, Alkarama and Al Wissam Humanitarian Assembly wrote to the United Nations Committee on Enforced Disappearances (CED) on 26 November 2015, hoping to clarify his fate and whereabouts.

On 25 November 2015, the United Nations Subcommittee on Prevention of Torture (SPT) announced that it will visit in Tunisia and Mauritania in 2016.

On 25 November 2011, Alkarama and Human Rights Guardians sent a communication to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the case of 49-year-old retired policeman Khalid Zain, his 29-year-old son Mohammad Zain and another family member,

On 24 November 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced of Involuntary Disappearances (WGEID) regarding the arrest by the Homeland Security of 45-year-old former Egyptian Air Force pilot Hany Mohamed Hassanin Sharaf on 18 November 2015.

On 20 November 2015, Alkarama sent a communication to the United Nations Special Rapporteur on torture and other cruel, inhuman or degrading treatment or punishment (SRT) regarding the case of 21-year-old student Ahmed Sayed Hussain Sharaf Ali Mohamed, who was arrested by members of the Riot Police in October 2014.

On 19 November 2015, Alkarama sent two communications, one to the United Nations Special Rapporteur on Torture and other cruel, inhuman or degrading treatment or punishment (SRT) and one to the UN Working Group on Enforced Disappearances (WGEID), regarding the case of 20-year-old Egyptian student

On 4 September 2015, during its 73rd session, the United Nations Working Group on Arbitrary Detention (WGAD) adopted an Opinion in which it acknowledges the arbitrary nature of the deprivation of liberty of Rachid Ghribi Laroussi.