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On 6 November 2014, Alkarama sent an urgent appeal to the Special Rapporteur on Torture (SRT) concerning the case of Sabri Ahmed Mehdi, a father of six detained and tortured since his arrest by the Egyptian authorities on 22 July 2014.

On 17 November 2014, Alkarama sent an urgent appeal the United Nations Working Group on Enforced and Involuntary Disappearances (WGEID) regarding the case of Yasser Ahmed Ahmed Abu Eita, a 23-year-old Egyptian citizen, disappeared since his arrest by the police forces in the streets of Damietta Port on 2 November 2014.

On 22 October 2014, Alkarama and AFD International wrote to the United Nations Working Group on Arbitrary Detention (WGAD) to alert them on the case of Mohamed Abdelhamid Abdelhamid Kharaba, a university professor arbitrarily detained in Alexandria's Al-Hadra prison since his arrest on 24 November 2013. His family claims that Kharaba's fight against corruption at the University of Alexandria is the reason for his arrest.

On 5 November 2014, Egypt's second Universal Periodic Review (UPR) was held at the Palais des Nations in Geneva. This process aims to assess the human rights record of each United Nations' Member State by the Human Rights Council (HRC). Since its first review in February 2010, Egypt has undergone major political upheavals.

Alkarama welcomes the release, on 6 November 2014, of 19-year-old student, Aliaa Tarek Mohammad Alsayed, whose family had not heard from since her abduction by the Egyptian security forces at the Al Azhar University campus in Cairo on 20 October 2014.

On 22 October 2014, Alkarama sent a communication to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the abduction of three Egyptian students.

On 17 October 2014, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) to bring to their attention the case of Mohamed Abdulhamid Ali, a 32 years old Egyptian citizen disappeared since his abduction by the National Security Forces on 24 September 2014.

On 1 October 2014, Alkarama sent an urgent appeal before the United Nations Special Procedures concerning the arbitrary detention and torture of Rawda Jamal Abd Al Azzem, an 18 year-old student arrested by the Egyptian police on 28 December 2013, in Nasr City.

On 23 September 2014, Alkarama sent an urgent appeal to the United Nations Special Rapporteur on Torture regarding the case of Ahmed Rashad, a 15 year-old teenager arrested on 16 May 2014 for taking part in a peaceful demonstration in the town of Zagazig, in lower Egypt.

On 8 and 9 October 2014, Alkarama delivered its key recommendations to the UN Member States' Permanent Missions for the second Universal Periodic Review (UPR) of Egypt, which will be held on 5 November 2014.