On 3 September 2015, Alkarama referred the case of six brothers to both the United Nations Special Rapporteur on Extrajudicial, Summary or Arbitrary Executions (SR SUMX) and the UN Special Rapporteur on Torture (SRT).

On 8 September 2015, Alkarama and Human Rights Guardians sent a communication to the United Nations Working Group on Enforced Disappearances (WGEID) regarding the case of 31-year-old Syrian construction worker, Ali Mostoo, who disappeared following his arrest, in April 2012, by forces of the Military Security Branch in I

On 2 September 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the cases of 20-year-old student, Abdelrahman Attef Hussein and 31-year-old employee Hani Said Kahla, both disappeared since their respective arrests by the police on 11 July and 19 August 2015.

On 8 September 2015, Alkarama and Human Rights Guardians sent a communication to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the disappearance of Anas Al Husseini, a Syrian Kurd arrested by the security forces in December 2012, tortured

On 28 August 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced and Involuntary Disappearances (WGEID) regarding the abduction of Mohamed Abdelaziz Farag, 54, his 18-year-old son, Abdelaziz Mohammed Abdelaziz Farag, and his 61-year-old brother, Ismael Abdelaziz Farag. All disappeared following their abduction, from their home in Shubra, by the Homeland Security on 23 August 2015.

On 8 September, Alkarama sent an urgent appeal to the United Nations Working Group on Arbitrary Detention (WGAD) regarding the case of Waleed Al Dod Al Mekki Al Hussain, a Sudanese national who has been deprived of his fundamental rights since his arrest by the Saudi General Intelligence forces on 23 July 2015.

On Monday 7 September 2015, Djameleddine Laskri entered its 24th year of arbitrary detention.

On 3 September 2015, Alkarama sent an urgent appeal to the United Nations Working Group on Enforced or Involuntary Disappearances (WGEID) regarding the enforced disappearance of journalist and member of the Muslim Brotherhood, Mosab Abdalla Abdelhamid Morsy Hamed, in early July 2015.

On 1 September 2015, Alkarama and Al Wissam Humanitarian Assembly sent a communication to the United Nations Committee on Enforced Disappearances (CED) regarding the case of a 35-year-old construction worker, Mohammad Al Jabouri, who disappeared in July 2015 following his abduction in Baghdad by the Iraqi Special Operations Forces, which operate under the control of the Ministry of Defence.

On 1 September 2015, Alkarama and Human Rights Guardians sent a communication to the United Nations Working Group on Enforced Disappearances (WGEID) regarding the cases of Abdul Rahman Al Jawalak and Ramez Al Deeb, who disappeared since their respective abductions from the Hama countryside by governmental forces between January and August 2012.